@import "variables.css";
@import "fonts.css";
@import "hero-section.css";
@import "support-section.css";
@import "page_menu.css";
@import "gaucher-disease.css";
@import "clinical-trial-program-overview-page.css";
@import "treatment-naive.css";
@import "treatment-experienced.css";
@import "treatment-shared.css";
@import "patients-profile-shared.css";
@import "charts.css";
@import "error.css";
@import "how-works.css";
@import "patient-population.css";
@import "think-vpriv.css";
@import "preparation-shared.css";
@import "preparation.css";
@import "takeda-support.css";
@import "administration.css";
@import "popups.css";
@import "contact-form.css";
@import "safety-tolerability.css";
@import "dosing-calculator.css";
@import "site-map.css";
@import "resources.css";


html {
  /* for set 1rem = 10px */
  font-size: 62.5%;
}

main {
  width: 100%;
  color: var(--color-text-dark);
}

h2 {
  margin-bottom: 0;
}

p {
  margin-bottom: 0;
}

sup {
  font-size: 0.6em;
}

a {
  color: var(--color-text-blue-light);
}

a:hover {
  color: var(--color-text-blue-light);
}

.color--text-pink {
  color: var(--color-text-pink);
}

.color--text-blue {
  color: var(--color-text-blue);
}

.color--text-blue-light-0 {
  color: var(--color-blue-0);
}

.color-text-blue--light {
  color: var(--color-text-blue-light);
}

.color--text-purple {
  color: var(--color-purple);
}

.color--text-yellow {
  color: var(--color-yellow-2);
}

.ssp-semibold {
  font-family: var(--ssp-semibold);
}

.ssp-bold {
  font-family: var(--ssp-bold);
}

.ssp-italic {
  font-family: var(--ssp-italic);
}

.ssp-bold-italic {
  font-family: var(--ssp-bold-italic);
}

.ssp {
  font-family: var(--ssp);
}

.exo-2 {
  font-family: var(--exo2);
}

.exo-2-light {
  font-family: var(--exo2-light);
}

.exo-2-medium {
  font-family: var(--exo2-medium);
}

.exo-2-semibold {
  font-family: var(--exo2-semibold);
}

.segoe-semibold {
  font-family: var(--segoe-semibold);
}

.bg-pink {
  background: var(--color-background-pink);
}

.bg-purple {
  background: var(--color-purple);
}

.bg-yellow {
  background: var(--color-yellow-2);
}

.bg-light-blue {
  background: var(--color-text-blue-light);
}

.bg-blue {
  background: var(--color-blue-4);
}

.no-wrap {
  white-space: nowrap;
}
.header {
  display: block;
  width: 100%;
  position: absolute;
  top: 0;
  left: 0;
  z-index: 100;
}

.header-mobile {
  display: none;
}

.references {
  margin-top: 5.2rem;
  font-size: 2.2rem;
  line-height: 2.2rem;
}

.references-header {
  margin-left: -2rem;
  font-family: var(--exo2-semibold);
}

.references-item:first-of-type {
  margin-top: 1.2rem;
}

.references-item {
  font-family: var(--ssp);
  font-size: 2.2rem;
  line-height: 2.8rem;
}

.references-item a {
  color: var(--color-blue-1);
}


.top-section {
  padding-top: var(--top-padding-hero);
}

.top-title {
  display: block;
  margin-inline: auto;

  font-family: var(--exo2);
  font-size: 4rem;
  line-height: 4.8rem;
  text-decoration: none;
  text-transform: uppercase;
  text-align: center;
  color: var(--color-text-pink);
}

.top-title-2 {
  display: block;
  margin-inline: auto;
  text-decoration: none;
  text-transform: uppercase;
  text-align: center;
  font-family: var(--ssp);
  font-size: 4rem;
  line-height: 3.5rem;
}

.top-subtitle {
  font-family: var(--ssp);
  font-size: 2.7rem;
  line-height: 3rem;
  text-align: center;
  margin-inline: auto;
  margin-top: 3.2rem;
}

.top-description {
  font-family: var(--ssp);
  font-size: 2.4rem;
  line-height: 3rem;
}

.top-image {
  position: absolute;
  right: var(--top-image-position-right);
  z-index: 2;
}

.notice {
  margin-top: 3.4rem;
  font-family: var(--ssp);
  font-size: 1.8rem;
  line-height: 2.2rem;
}

.pagination-buttons {
  height: 4.6rem;
  margin-top: 2.4rem;
  display: flex;
  justify-content: flex-end;
  gap: 3rem;
}

.button-pagination,
.button-download {
  border: 1px solid var(--color-blue-4);
  border-radius: 10rem;
  background: var(--color-white);
  color: var(--color-text-blue);
  padding: 0.8rem 1.8rem 0.8rem 0.7rem;

  display: flex;
  align-items: center;
  gap: 0.9rem;

  overflow: hidden;
  position: relative;

  transition: 0.5s transform ease-in-out, 0.5s color;
  z-index: 0;
}

.button-pagination::after,
.button-download::after {
  background-color: var(--color-purple);
  border-radius: 10rem;
  content: '';
  display: block;
  height: 100%;
  width: 100%;
  position: absolute;
  left: 0;
  top: 0;
  transform: translate(-100%, 0);
  transform-origin: top left;
  transition: 0.5s transform ease-out;
  z-index: -1;
}

.button-pagination:hover::after,
.button-download:hover::after {
  transform: translate(0, 0);
}

.button-pagination:hover,
.button-download:hover {
  color: var(--color-white);
}

.button-pagination::after {
  background-color: var(--color-purple);
}

.button-download::after {
  background-color: var(--color-blue-4);
}

.button-pagination .direction,
.button-download .download {
  position: relative;
  width: 3rem;
  height: 3rem;
  flex: 0 0 3rem;

  background: var(--color-purple);
  border-radius: 50%;
  border: 2px solid var(--color-white);
}

.button-download .download {
  background: var(--color-blue-4);
  background-image: url("/images/newButtonsSvgs/download.svg");
  shape-rendering: crispEdges;
}

.button-pagination .direction::before,
.button-download .download::before {
  position: absolute;
  content: '';
  top: 50%;
  left: 50%;

  width: 0.8rem;
  height: 1.6rem;
}

.button-download .download::before {
  width: 1.2rem;
  display: none;
  background: url(../images/Download.svg);
  background-size: 100%;
  background-repeat: no-repeat;
  background-position: center;
  transform: translate(-50%, -50%);
}

.button-next .direction {
  background-image: url("/images/newButtonsSvgs/right-purple.svg");
}

.button-next .direction::before {
  background: url(../images/arrow-right.svg);
  display: none;
  background-size: 100%;
  background-repeat: no-repeat;
  background-position: center;
  transform: translate(-50%, -50%);
}

.button-previous .direction {
  background-image: url("/images/newButtonsSvgs/left-purple.svg");
}

.button-previous .direction::before {
  display: none;
  background: url(../images/arrow-right.svg);
  background-size: 100%;
  background-repeat: no-repeat;
  background-position: center;
  transform: translate(-50%, -50%) rotate(-180deg);
}

.button-pagination .text,
.button-download .text {
  font-family: var(--exo2-semibold);
  font-size: 1.7rem;
  line-height: 2.3rem;
  text-decoration: none;
}


.brochure-and-buttons {
  margin-top: 4.3rem;
  display: flex;
  justify-content: space-between;
}

.brochure-cover {
  max-width: 45%;
  padding: 2rem 2rem 2rem 15.8rem;

  background-color: var(--color-silver-400);
  border: 2px solid var(--color-silver-300);
  border-radius: 10px;

  position: relative;
  display: flex;
  flex-direction: column;
  justify-content: space-between;
  gap: 2rem;
}

.brochure-image {
  position: absolute;
  left: 2rem;
  top: 1.9rem;
}

.brochure-description {
  font-family: var(--ssp);
  font-size: 2rem;
  line-height: 2.2rem;
}

.brochure-cover .button-download {
  max-width: max-content;
  margin-top: 2rem;
}

.brochure-and-buttons .pagination-buttons {
  margin-top: 10.8rem;
  max-width: 48%;
}

.custom-border {
    border: 1px solid var(--color-text-dark);
}

.guide-cover {
  display: flex;
  justify-content: space-between;
  gap: 2rem;

  padding-inline: 2rem;
  background-color: var(--color-silver-400);
  border: 2px solid var(--color-silver-300);
  border-radius: 1rem;

  position: relative;
}

.quide-wrapper {
  display: flex;
  flex-direction: column;
  justify-content: space-around;
}

.guide-description {
  font-family: var(--ssp);
  font-size: 2rem;
  line-height: 2.4rem;
}

.section-header {
  font-family: var(--exo2);
  font-size: 3.2rem;
  line-height: 4.3rem;
  text-transform: uppercase;
}

.section-text {
  font-family: var(--ssp);
  font-size: 2.4rem;
  line-height: 3rem;
}

.section-text--important {
  font-family: var(--ssp-semibold);
  font-size: 2.5em;
  line-height: 2.2rem;

}

.list {
  font-family: var(--ssp);
  font-size: 2.4rem;
  line-height: 3rem;

  padding-left: 0;
}

.list-header {
  margin-bottom: 2rem;
}

.list-item {
  list-style-type: none;
  padding-left: 1.6rem;

  position: relative;
}

.list-item:not(:last-of-type) {
  margin-bottom: 1.6rem;
}

.list-item::before {
  content: '';
  position: absolute;
  left: 0;
  top: 1.2rem;

  width: .6rem;
  height: .6rem;
  border-radius: 50%;

  background: var(--color-background-pink);
}

.list-blue .list-item::before {
  background: var(--color-blue-4);
}

.list-blue-light-0 .list-item::before {
  background: var(--color-blue-0);
}

.list-item p {
  margin-top: 1.6rem;
}

.button--contact-rep {
  position: absolute;
  right: var(--inline-padding-outland);
  right: calc(var(--inline-padding) - 12rem);
  bottom: 0;
  background: none;
  border: none;
  cursor: pointer;
}

.section-content {
  position: relative;
  z-index: 1;
}

.background {
  position: absolute;
  top: 0;
  left: 0;

  width: 100%;
  z-index: 1;
}

sup {
  white-space: nowrap;
}
.text-20 {
    font-size: 20px;
    line-height: 1.2;
}
.one-path-info .content-text-part p.text-20:last-child {
    font-size: 17px;
}
.patient-bullet-points.mateo p {
    font-size: 17px;
    line-height: 1.3;
    color: var(--color-blue-4);
    padding-left: 35px;
    margin-top: 15px;
}


.error-input, .error-input:focus {
    border: 2px solid #E92076;
}

.brochure_btns .button-download p {
    font-size: 1.5rem;
}

.patient-footer-shared-desktop .looking-to-start .first-row {
    height: 19rem;
}

.bg-image.mateo {
    width: 100rem;
    top: 0;
    background-position: left 4rem bottom;
}

a.button-download.text-decoration-done {
    text-decoration: none;
    width: fit-content;
}

.cursor-pointer {
    cursor: pointer;
}

.resources.for_yourpatients {
    max-width: none;
}

.button-download p a.text-decoration-done {
    text-decoration: none;
    color: var(--color-text-blue);
}

.button-download:hover p a.text-decoration-done {
    color: white;
}

.header-menu--item.active .item-sub-menu {
    z-index: 1;
}
@media screen and (min-width: 2400px){
  :root {
    --top-padding-hero: 23rem;
  }

  .scroll-arrow-bigger-population {
    transform: translate(1060px, 1144px) scale(0.9);
  }

  .scroll-arrow-bigger {
    transform: translate(1060px, 1855px) scale(0.9);
  }

  .scroll-arrow-bigger-resource {
    transform: translate(1060px, 1348px) scale(0.8);
  }

}

@media screen and (max-width: 1200px) {
  :root {
    --inline-padding: 2rem;
    --inline-padding-outland: 1rem;
    --top-image-position-right: var(--inline-padding-outland);
  }
}

@media screen and (max-width: 1200px) {

  .blue-blob,
  .purple-blob,
  .pink-blob,
  .green-blob,
  .yellow_blub,
  .hero-blob {
    display: none;
  }

  .header {
    display: none;

  }

  .header-mobile {
    display: block;
  }

  .button--contact-rep {
    display: none;
  }

  .top-title {
    margin-inline: 0;
  }

  .top-subtitle {
    margin-inline: 0;
  }

  .brochure-and-buttons .pagination-buttons {
    flex-direction: column;
  }

  .brochure-cover {
    max-width: 50%;
  }

  .list {
    font-size: 2.2rem;
    line-height: 2.4rem;
  }
  .list-item::before {
    top: 1rem;
  }
  .pagination-buttons {
    height: auto;
  }
}

@media screen and (max-width: 820px) {

  .top-title {
    font-size: 3rem;
    line-height: 3.4rem;
  }

  .top-title-2 {
    font-size: 2.8rem;
    line-height: 3rem;
  }

  .top-subtitle {
    font-size: 2.2rem;
    line-height: 2.4rem;
  }

  .top-description {
    font-size: 2rem;
    line-height: 2.2rem;
  }

  .brochure-and-buttons .pagination-buttons {
    flex: 1;
    flex-direction: row;
    max-width: 100%;
    margin-top: 2rem;
  }

  .brochure-cover {
    max-width: 100%;
    flex: 0
  }

  .brochure-and-buttons {
    margin-top: 4.3rem;
    display: flex;
    flex-direction: column;
    gap: 2rem;
    justify-content: space-between;

  }

  .button-download .text {
    text-align: left;
  }

  .references {
    margin-top: 3rem;
    font-size: 2rem;
    line-height: 2rem;
  }

  .references-item {
    font-size: 1.8rem;
    line-height: 2rem;
  }

  .section-header {
    font-size: 2.4rem;
    line-height: 2.8rem;
  }

  .section-text {
    font-size: 2rem;
    line-height: 2.2rem;
  }

  .section-text--important {
    font-size: 2.1rem;
    line-height: 2.2rem;
  }
  .list {
    font-size: 1.8rem;
    line-height: 2rem;
  }
.text-20 {
    font-size: 18px;
    line-height: 1.2;
}
.one-path-info .content-text-part p.text-20:last-child {
    font-size: 16px;
}
  .list-item::before {
    top: 0.8rem;
  }

  .guide-cover {
    gap: 1rem;
    padding: 1rem;
  }
  .guide-description {
    font-size: 1.8rem;
    line-height: 2rem;
  }
  .scroll-arrow-bigger-population {
    transform: translate(1280px, 1085px) scale(1.6);
  }

  .scroll-arrow-bigger {
    transform: translate(1280px, 1810px) scale(1.6);
  }

  .scroll-arrow-bigger-resource {
    transform: translate(1280px, 1353px) scale(1.7);
  }
    .patient-bullet-points.mateo p {
        font-size: 15px;
        padding-left: 15px;
    }
    .bg-image.mateo {
        top: 1.5rem;
    }
}

@media screen and (max-width: 576px) {

  .top-title {
    font-size: 2.5rem;
    line-height: 2.6rem;
  }

  .top-title-2 {
    font-size: 2.4rem;
    line-height: 2.4rem;
  }

  .top-subtitle {
    font-size: 1.8rem;
    line-height: 2rem;
  }

  .top-description {
    font-size: 1.6rem;
    line-height: 1.6rem;
  }

  .top-image {
    left: 60%;
    bottom: 0.2rem;
  }

  .list-header {
    margin-bottom: 1rem;
  }

  .list {
    font-size: 1.6rem;
    line-height: 1.8rem;
  }
  .list-item::before {
    top: 0.6rem;
  }

  .list-item:not(:last-of-type) {
    margin-bottom: 0.8rem;
}

  .section-header {
    font-size: 2rem;
    line-height: 2.2rem;
  }

  .section-text {
    font-size: 1.6rem;
    line-height: 1.8rem;
  }

  .section-text--important {
    font-size: 1.7rem;
    line-height: 1.7rem;
  }

  .notice {
    margin-top: 2.5rem;
    font-size: 1.6rem;
    line-height: 1.8rem;
}

  .pagination-buttons {
    display: flex;
    align-items: flex-end;
    flex-direction: column;
    height: auto;
    gap: 1.5rem;
  }

  .brochure-and-buttons {
    margin-top: 3rem;
  }

  .brochure-and-buttons .pagination-buttons {
    flex-direction: column;
    margin-top: 0;
  }

  .brochure-cover {
    padding: 1rem 1rem 1rem 11rem;
  }

  .brochure-cover .button-download {
    margin-top: 1rem;
  }
  .brochure-image {
    position: absolute;
    left: 1rem;
    top: 1rem;
    max-height: calc(100% - 2rem);
  }

  .brochure-description {
    font-size: 1.7rem;
    line-height: 1.7rem;
  }

  .guide-description {
    font-size: 1.6rem;
    line-height: 1.6rem;
  }

  .guide-description br {
    display: none;
  }

  .quide-wrapper {
    padding-block: 1rem;
    gap: 2rem;
  }

  .button-pagination,
  .button-download {
    padding: 0.3rem 1rem 0.3rem 0.7rem;
    gap: 0.5rem;
  }

  .button-pagination .text,
  .button-download .text {
    font-family: var(--exo2-semibold);
    font-size: 1.4rem;
    line-height: 1.4rem;
  }

  .scroll-arrow-bigger-population {
    transform: translate(1280px, 1065px) scale(3.1);
  }

  .scroll-arrow-bigger1 {
    transform: translate(1280px, 930px) scale(3.1);
  }

  .scroll-arrow-bigger {
    transform: translate(1280px, 1790px) scale(3.1);
  }

  .scroll-arrow-bigger-resource {
    transform: translate(1280px, 1326px) scale(3.1);
  }

  .references {
    margin-top: 2rem;
    font-size: 1.7rem;
    line-height: 1.8rem;
  }

  .references-item {
    font-size: 1.4rem;
    line-height: 1.6rem;
  }

}

@media screen and (max-width: 355px) {
  :root {
    --inline-padding: 1rem;
    --top-pading-mobile: 14rem;
  }

  .top-section {
    padding-bottom: 21rem;
  }


  .top-image {
    max-height: 18rem;
    width: auto;
  }

  .notice {
    margin-top: 3.4rem;
    font-size: 1.4rem;
    line-height: 1.6rem;
  }

  .brochure-cover {
    padding: 1rem 1rem 1rem 11rem;
  }

  .brochure-image {
    left: 1rem;
    top: 1.4rem;
    max-width: 9rem;
  }

  .brochure-cover .button-download {
    margin-top: 1rem;
  }

  .guide-cover {
    gap: 0.8rem;
    padding-inline: 0.8rem;
  }
}

* {
  scroll-margin-top: 40px;
}

.section[id] {
  scroll-margin-top: 50px;
}

/*.d-none {
    display: none !important;
}*/

/*start form css*/
.portalParent.cAPS_DataEntry_Horizontal_Menu_Container .contentHeader {
    margin-top: 0 !important;
}